Modern approaches to the diagnosis and treatment of polycystic ovary syndrome in adolescence

Тhe diagnosis of polycystic ovary syndrome (PCOS) in adolescence still raises many questions. The problem is that the characteristics normal puberty often coincide with symptoms PCOS. article presents criteria a menstrual cycle, clinical and laboratory hyperandrogenism. In latter, most informative indicators are determination index free testosterone androstenedione, assessment total relatively low sensitivity. Clinical hyperandrogenism adolescents includes only severe acne hirsutism. level antimullerian hormone has no independent significance. Irregular cycles during first year after menarche represent period puberty. At second third , less than 21 days more 45 considered irregular, from fourth – 35 days. From menarche, irregularities to be 90 for any cycle. Primary amenorrhea indicated by absence at 15 years, or 3 years telarche. Ultrasound not used as criterion PCOS 8 due high frequency ovarian multifollicularity adolescence. Therefore, adolescent girls presence disorders may diagnosed «PCOS. Phenotype B» (ultrasound signs taken into account). Adolescents who have but do meet diagnostic risk important stage therapy lifestyle modification, normalization body weight metabolic processes. Combined oral contraceptives prescribed direct purposes (contraception), off-label diagnosis, also «risk group», which involves treatment irregular / effect changes, proper nutrition correct addition combined metformin, inositol etc.